112 L. B. WINTER AND W. SMITH.
REFERENCES.
(1) Minkowsky. Arch. f. exp. Path. u. Pharm. 21. p. 1. 1886.
v. Mering and Minkowsky. Cntrlb. f. klin. Med. 10. p. 393. 1889.
(2) Clark. Journ. Exp. Med. 24. p. 631. 1916.
(3) Clark. Ibid. 26. p. 731. 1917.
(4) Embden and others. Zeit. f. physiol. Chem. 93.
(5) Folin and Wu. Journ. Biol. Chem. 38. p. 81. 1919.
(6) Folin. Ibid. 51. p. 419. 1922.
(7) Fischer. Berichte, 23. p. 3688. 1890.
(8) Wood and Berry. Camb. Phil. Journ. 46. p. 103. 1904.
(9) Hewitt and Pryde. Bioch. Journ. 14. p. 395. 1920.
(10) Cooper and Walker. Ibid. 16. p. 455. 1922.
(11) Oppler. Zeit. f. physiol. Chem. 64. p. 393. 1910; Ibid. 75. p. 71. 1911.
(12) Armstrong and Hilditch. Journ. Chem. Soc. 115, p. 1410. 1919.
(13) Nef. Ann. d. Chem. u. Pharm. 357. p. 294. 1907.
PROTOCOLS.
ANIMALS. One experiment only is given of those made on each kind of animal.
Initial polarimeter Final Copper reducing
reading reading value
R. R. R.
Rabbit, 50 c.c. blood . 02 07 . 08
Cat, 80 c.c. blood ... . 03 08 . 08
Sheep, 100 c.c. blood . 04 . 08 - 08
Ox, 100 c.c. blood ... 03 . 12 . 12
EXPERIMENTS ON MAN.
Polarimetric Copper
readings on reducing
successive days value Bang
R. R. %j
H. L. W. Normal. 95 c.c. blood . .. . 07, 08, 09, .11, 11 i 11
H. L. W. 150 gm. fructose. 100 c.c. blood 04, 06, 09, *10, *10 10 13
G. rF. T. Normal. 85 c.c. blood ... 03, 06, '05, 10, 09 .10
G. F. T. 150 gm. glucose. 55 c.c. blood ... 04, 06, 08, 08, 08 08 13
H. M. Normal. 72 c.c. blood ...02, 03, 08, 10, .10 12 .10
J. C. C. P. Normal. 100 c.c. blood ... 20, 19, 20, 18 . 21 - 17
J. B. S. H. Normal 70 c.c. blood ... 08, .09, -10, .10, 10 ' 10 . 17
G. M. D. Normal. 70 c.c. blood . .. 02, .05, 08, 08, 08 -08 .08
W. S. 100 gm. glucose. 65 c.c. blood ... 05, 07, o9, 08, 08 08 14
L. B. W. Normal. 100 c.c. blood ... .07, .11, .13, .14, 14 .14 .09
L. B. W. 100 gm. glucose. 55 c.c. blood ... 04, 05, 08, 09,09, 09 13
L. 13. W. 150 gm. fructose. 100 c.c. blood 06, '08, '10, '13, '14 . 16 . 12
Diabetic (Dr J. Aldren Wright's patient).
18 c.c. blood . ......11, 10, 09, 09 09
Diabetic (Dr J. Aldren Wright's patient).
20 c.c. blood ....... .. ... . 11, 10, 10, 10 *10 --
Diabetic (Dr G. Graham's patient). 21 c.c.
blood . ... ... .... . . · 11, · 10, 08, 08 08 08 -
Diabetic (Dr G. Graham's patient). 13 c.c.
blood .. ..... ... ... 07, 06, '05, 05 *03 -
G.P. (cerebral hæemorrhage. Dr Lloyd-
Jones' patient). 100 c.c. blood ... 21, .26, .24, .25 . 25