RELATION OF PANCREATIC EXTRACT TO SUGAR, IOI
typical example of the Froehlich typus or the so-called dystrophia
adiposo-genitalis of Bartels.
The patient was placed on the high protein diet of Folin and
the following tables contain the data obtained in this study.
The high undetermined nitrogen and neutral sulphur of the urine,
can readily be noted, while the absorption of fat and protein
Summary of data pertaining to total nitrogen and fat metabolism.
Total Nitrogen. Feces. Fat.
Total Nitrogen. _
at. Ingested, Excreted. Balance, Fat, a In- Pacent.
Grams. Grams. Ga. Gramsa.. Foîd Pe' Ce=t. tt FtbAdAb
Grams. }of Total ~as a b
6/26 z8.2 17.9 +0.3 2.2 I.8 9.9 I40 98.4
6/27 18.6 I8.I +0.5 2.2 1.8 9.7 I40 98.4
6/28 I8.3 7.5 +0.8 2.2 I.8 9.9 140 98.4
6/29 I8.I I7.9 +0.2 I.8 2.1 11.6 146 98.8
6/30 17.6 I7.4 +0.2 I.8 2.1 II.g I46 98.8
7/I '7.8 17.8 0 1.8 2.1 II.9 I46 98.8
Total I08.6 I06.6 +2.0 12.00 II.70 _ 858 -
lO. +2. la OO 11 7 85
Average II I-î-'.7+ +0.33 2.00 1.95 10.8 143 98.6
The relation of pancreatic extract to the sugar of the blood.
By ERNEST L. SCOTT.
[From the Department of Physiology of Columbia University.]
In January, I912, I reported a preparation of pancreas which
when injected intravenously into dogs that had been rendered
diabetic by pancreatectomy, lowered both the output of sugar
and the D/N ratio. This preparation seemed to offer a ready
means of attack for several of the problems bearing on the relation
of the pancreas to sugar metabolism. Possibly the simplest of
these is the relation between the amount of sugar present in the
blood and the abundance of the pancreatic hormone present, and
this is a preliminary report of my work on this subject.
Cats were killed and their blood was collected. The protein
was removed and the blood was decolorized by a modification of
the phosphotungstic acid method reported by Oppler. In deter-