Reprinted from
TEE CANADIAN MEDICAL ASSOCIATION JOURNAL
September, 1924
SOMIE RECENT ADVANCES IN
ENDOCRINOLOGY*
J. B. COLLIP, Ph.D., D.Sc.
Professor of Biochemistry, University of
Alberta, Edmonton
THERE Iprobably is no department of medical
science which is receiving more attention
than that concerning the endocrines, nor in-
deed is there any field of research which
promises to be more fruitful from the practical
as well as from the theoretical standpoint as
this field of endocrinology. If one might ven-
ture a prophecy, one might say that it will be
along the lines of endocrinology and meta-
bolism that the science of medicine vill in the
main advance in the next twenty-five years.
It is my purpose to-night to aiscuss some of
the more recent Twork relating to the ductless
glands.
THE PANCREAS
Ever since the classical experiments of
Mering and Minkowski' in 1889 who de-
monstrated that complete removal of the pan-
creas of normal dogs is followed by the
development of a condition resembling in prac-
tically all respects severe diabetes mellitus in
man, the hypothesis that the pancreas exer-
cises an anti-diabetic function by virtue of an
internal secretion which it produces, has been
accepted by numerous investigators. That this
is so is evidenced by the numerous attempts
*Gordon-Bell memorial lecture delivered before the
Winnipeg Medical Society, April 11th, 1924.