RECENT WORK ON INSULIN *
C. H. BEST
Insulin Division, Connaught Laboratories, University of Toronto
INTRODUCTION
The discovery of insulin, which was reported some two
years and a half ago, has been followed by publications from an
extremely large number of investigators. It is interesting to
note that many groups of workers have reported several times
on this subject. It is quite obvious, therefore, that insulin is
an interesting theme which is not easily exhausted. The large
amount of literature which has accumulated makes it necessary
to limit our discussion today to certain phases of the recent
developments. It will be advantageous to dwell more particu-
larly upon those aspects of insulin in which our laboratory is
especially interested and which, at the present time, we are
actively investigating. This will give me the opportunity of
submitting to you the results of our recent experiments, as well
as to review some of the published work of other observers. I
shall try to touch upon phases of insulin other than those which
have been very completely discussed in recent reviews.
THE PREPARATION OF INSULIN
The comparatively simple method for the preparation of
insulin as originally published from Toronto (1) has been fol-
* Read at the Eighth Annual Session of the Association for the Study of In-
ternal Secretions, Chicago, June 9, 1924.