REPORT OF AUTOPSY FINDINGS ON DO NO. 33
We made a very careful examination of this dog with the object of
determining if any pancreatic tissue had been left from the operation, or if
possible, an accessory pancreas were present.
The area formerly occupied by the pancreas showed no gross evidence
of pancreatic tissue. There were a number of firm fibrous adhesions about
the duodenum. These were sectioned, and on microscopic examination showed
no evidence of pancreatic tissue remaining in them.
The duodenum was then examined and nothing abnormal found except
for a small nodule (see Fig. 3) about 3 mm. in diameter situated in the wall
at the mesenteric attachment and 10 cms. below the pylorus. This on micro-
Fig. 3.-Section of wall of duodenum a et seat of pancreatectomy.
scopic examination was found to consist of what is apparently a nodule of
pancreatic tissue, lying in the submucosa. Serial microscopic sections of this
however, failed to show the presence of any Islands of Langerhans.
No other gross or microscopical evidences of pancreatic tissue could be
(s) W. L. Robinson,
Toronto General Hospital.
To study the effect of an intravenous injection of whole gland (normal
beef pancreas) extract upon the blood pressure of a diabetic animai, Dog
27 was anestethized and its blood pressure recorded. (See Fig 4.) After
the intravenous injection of five c.c. of extract, the blood pressure fell ap-
proximately 50 mm., but regained its original level in less than two minutes.
The effect of a similar dose of extract upon the blood sugar of an unanesthe-
tized diabetic animal would have lasted for at least six hours, and the lowest