JOURN. OF METAB. RESEARCH.--August Issue :: Galley 15
SUMMARY OF PUBLICATIONS ON INSULIN TO DATE

Dr. Frederick G. Banting first conceived the idea of preparing a potent extract from the atrophied pancreas, and carried it out successfully in collaboration with C. H. Best. Later, J. B. Collip, E. C. Noble, J. K. Hepburn and J. K. Latchford became associated in the work. The experiments on animals were conducted in the Department of Physiology under the direction of Professor J. J. R. Macleod, and received the aid and support of Professor V. E. Henderson of the Department of Pharmacology, on whose staff Banting held an appointment. The clinical application was then made, with the assistance of W. R. Campbell and A. A. Fletcher, in the clinic of Professor Duncan Graham in the Toronto General Hospital and in other institutions. Through the support of the Connaught laboratories, under the direction of Prof. J. G. Fitzgerald and Prof. R. Defries, facilities were obtained for the first small production for clinical trials, with insulin prepared by a method elaborated by J. B. Collip. The rapid and brilliant achievements bear witness to the genius and energy of the young investigators and the experience and skill of their older advisers and associates.
As the discovery of an effective non-toxic pancreatic extract is literally epoch-making, and as few readers have easy access to all the journals in which the early papers have appeared, a useful purpose may be served by the following abstract of all the publications on this subject up to the present. Thanks are due to the various journals for permission to quote much of these papers verbatim.