SUMMARY OF PUBLICATIONS ON INSULIN TO DATE.
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Dr. Frederick G. Banting first conceirved the idea of preparing a potent extract from the atrophied panereas, and carried it out
successfully in collaboration with C.H. Best. Later, J.B. Collip, E.C. Noble, J. Hepburn and J.K. Latchford became associated in the work. The experiments on animals were coenducted in the Department of Physiology of the University of Toronto under the direction of Professor J.J.R. Macleod, and received the aid and support of Professor V.E. Henderson of the Department of Pharmacology, on whose staff Banting held an appointment. The clinical application was then made, with the assistanee of W.R. Campbell and A. Hetcher, in the Toronto General Hospital and other institutions. Through the support of the Connaught Laboratories, under the direction of Prof. J.G. Fitzgerald and Prof. R. Defries, facilities were obtained for the first small produotion for clinical trials. The rapid and brilliant achievements bear witness to the genius and energy of the young investigators and the experience and skill of their older advisers and associates.
As the discovery of an effective, non-toxic panereatic extract is literally epoc-making, and as few readers have easy access to all the journals in which the early papers have appeared, a useful purpose may be served by the following abstract of all the publications on this subject up to the present. Thanks are due to the various journals for permission to quote the main parts of these papers verbatim.