University of Toronto
Toronto, Canada
Department of Physiology

writing because we have not despaired
of securing more typical cases and because
we wish you to receive the more
significant results without the delay
which the preparation of the others would
cause.
We made an extract from a
pancreas, the ducts of which had been
tied for five weeks. We followed your
directions in preparing the extract - chilled
[?], [?] [Ruger's solution?] etc. Our first
trial was on a dog (410) whose pedicle
had been removed on July 18th. This
animal was running a blood sugar
7.2 and a G:N ratio of about 2:1. We
are inclosing a chart showing her
history. The extract seemed to have
a marked effect. The second trial was
on a dog (406) which was in a state of
coma. The chart shows the
shows the significant part of her
history.
Our most convincing experiment